Given the choice I go for top tier fems. They have the best end product imho.
Autos have their place if time is an issue (like my new run is all auto because I have to finish it by July or the heat will destroy them). But in my (albeit limited) experience I think the end product is not quite as good as photos.
I haven’t bothered with regs for the simple reason I only have a small tent and don’t have the ability to grow 8-10 plants through to sexing. Regs I think are best for breeding (or maybe some rare genetics - some of the small breeders only offer regs), which I have not got into yet.
But for my next runs I am going to be looking into pheno hunting, the variance I’ve seen between plants of the same strain has been crazy. I want to try to make sure they are consistently good in future rather than a lottery of which ones are gonna be good. I just want to grow consistently A+ tier bud, is that too much to ask lol. So I might have to get a new tent to keep mothers in. But that’s for another thread, for now I have my hands full drying my last run and starting the auto run…